Cecilia Diniz Behn
Associate Professor, Applied Mathematics and Statistics
- PhD, Mathematics. Boston University, Boston, MA (2006)
- MA, Mathematics, University of Texas, Austin, TX (2002)
- AB, Mathematics, magna cum laude, Bryn Mawr College, Bryn Mawr, PA (1999)
- Budapest Semesters in Mathematics, Technical University of Budapest, Budapest, Hungary (Spring 1998)
My research applies multiscale mathematical modeling to investigate key research questions in metabolism, sleep, and circadian rhythms. Specifically, I model key dynamics in whole-body metabolism including changes in glucose, glycerol, and insulin; sleep and circadian (~24 h) neurophysiology; and the diverse interactions among these systems. Dysregulation of metabolism and/or sleep has dramatic implications for human health, and the complex ways in which these systems interact, both on a mechanistic and on a behavioral level, are just beginning to be understood. My research in mathematical and computational neuroscience focuses on understanding neurophysiologic mechanisms for sleep/wake regulation and my work in whole-body glucose-insulin dynamics focuses on insulin resistance in adolescents.
Mathematically, my research contributes to the development of novel techniques to understand high-dimensional multiscale systems of differential equations; analyze connections between structure and dynamics of general networks; and investigate dynamics at the interface of deterministic and stochastic behavior.
During the course of my graduate training in the Department of Mathematics and the Center for BioDynamics at Boston University and my postdoctoral training in the Division of Sleep Medicine at Harvard Medical School and the Department of Mathematics at the University of Michigan, I have developed a strong, externally-funded research program in applied math with vital connections to experimentalists and clinicians.
Current Research Projects
- Multiple time scales in the interactions between sleep and circadian rhythms
- Glucose-insulin dynamics tissue-specific insulin resistance
- Orexin/hypocretin neurons and their role in stabilizing sleep-wake behavior
- Stochastic and deterministic contributions to the fine architecture of sleep-wake behavior
- Math 498/598 Mathematical and Computational Neuroscience